Assessment of genetic integrity, splenic phagocytosis and cell death potential of (Z)-4-((1,5-dimethyl-3-oxo-2-phenyl-2,3dihydro-1H-pyrazol-4-yl) amino)-4-oxobut-2-enoic acid and its effect when combined with commercial chemotherapeutics

Abstract The increased incidence of cancer and its high treatment costs have encouraged the search for new compounds to be used in adjuvant therapies for this disease.This study discloses the synthesis of (Z)-4-((1,5-dimethyl-3-oxo-2-phenyl-2,3dihydro-1H-pyrazol-4-yl) amino)-4-oxobut-2-enoic acid (IR-01) and evaluates not only the action of this co

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MAXIMUM AUTOMOBILE ACCELERATION

Problem.The disadvantage of current dependences for determining the acceleration indicators at engine maximum brake power and driving tire-to-surface friction coefficients is that they are adequate only if the engine and transmission parameters provide power input to the drive wheels rolling without slipping regardless to speed.To Hydraulic Air Sti

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Pediatric oncology-hematology outreach: Evaluation of patient consultations by teleconferences between Indonesian and Dutch academic hospitals

Background: Improving the quality of care Kitchen Boa in resource limited settings through an outreach program is challenging.Teleconferencing is increasingly being used and considered a breakthrough in medical education.We evaluated adherence with childhood oncology-hematology teleconferences between two academic hospitals in Indonesia and Netherl

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